Lung growth and aging

Isometric growth of lungs and airways in healthy individuals

Isometric growth of lungs and airwaysMaterial
We now consider the data collected in about 700 pupils of secondary schools, who were investigated at 6 month intervals for up to 7 years. The great majority never experienced respiratory symptoms. Lung disease during the study was quite rare. A number of adolescents, however, had experienced respiratory symptoms before the age of 6 year; the nature of the underlying disorder could only rarely be elucidated retrospectively.

As in the children with asthma there was no difference in the growth rate judged by k in the equation MEF = a·Vk. There was, however, a conspicuous difference in the level of MEF (represented by 'a' in the equation). This is shown here by displaying FEV1 as a percentage of the total lung capacity. The FEV1 is the volume forcibly exhaled in one second, in fact a time averaged flow that is to some extent comparable to MEF. The FEV1 is the index used most frequently to assess airway obstruction.


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