Lung growth and aging

Longitudinal study

Experimental setup to test whether lungs and airways grow isometricallyWe can test the hypothesis of isometric growth of lungs and airways as follows.

Such a study was performed in hundreds of adolescent boys -and girls. They took part in a 7 year follow-up study, during which lung volumes and flow-volume curves were obtained at half year intervals. A similar study was also performed in a (smaller) group of children with asthma.

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  1. Merkus PJFM, van Pelt W, van Houwelingen JC, van Essen-Zandvliet LEM, Duiverman EJ, Kerrebijn KF, Quanjer PH. Inhaled corticosteroids and growth of airway function in asthmatic children. Europ Respir J 2004; 23: 861-868.
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